Gel – combined preparation for external use, the pharmacological properties of which are caused by the action of its constituent materials.
Heparin – anticoagulant direct action, a natural anticoagulant factor in the body – has anti-inflammatory action, promotes regeneration of connective tissue by inhibiting the activity of hyaluronidase; prevents thrombosis, activates the fibrinolytic properties of blood; improved local blood flow.
Dexpanthenol – provitamin B 5 – in the skin is converted into pantothenic acid, which is a part of coenzyme A, which plays an important role in the processes of acetylation and oxidation; improving metabolism, dexpanthenol promotes regeneration of damaged tissues; improves absorption of heparin.
Troxerutin – angioprotective means; has a P-vitamin activity, in particular, it reduces vascular tissue permeability and capillary fragility, helps normalize microcirculation and tissue trophism and reduces congestion in the veins and paravenoznyh tissues has decongestant and anti-inflammatory effects.
Moreover, due to the presence of preservative, antiseptic phenylethyl alcohol the drug has a bactericidal and fungicidal effect, contributing to the prevention of infection of the wound surface. The composition of helium provides the basics moderate hyperosmolar drug properties.
- edematous mikrotsirkuljatorno pain and trophic disorders of the lower extremities due to venous insufficiency (varicose veins, acute and chronic thrombosis, post-thrombotic syndrome, chronic lymphostasis);
- soft tissue injuries (bruises, sprains, strains);
- to accelerate the granulation and epithelialization of trophic ulcers in the regeneration phase (in the absence of a pronounced exudation).
- Hypersensitivity to the drug,
- open infected wounds or wounds with profuse exudation.
Application of pregnancy and lactation
durabolin injection ® is not contraindicated during pregnancy and lactation.
Dosing and Administration
durabolin injection ® coated with a thin layer on the affected area and around 2-3 times a day, evenly distributed over the surface of the skin with light rubbing motion until completely absorbed. The course of treatment is 2-3 weeks. The need for continued treatment determined by the attending physician based on the severity of the pathological process and the results of clinical tests. At relapse of the disease, treatment can be carried out 2-3 times a year.
In trophic ulcers with low exudation before using the product wound surface is cleaned of exudate and necrotic tissue, if necessary, washed with a solution of 3% hydrogen peroxide, furatsilina 1: 5000 or chlorhexidine bigluconate 0 05% and dried. The gel is applied evenly a thin layer so that the entire surface was covered struck drug and a sterile gauze bandage applied. Change of dressings is carried out 1 time per day. In the open method of treatment drug is applied 12 times per day. Duration of treatment is determined by the dynamics of epithelialization.
There are local manifestations of allergic reactions (rash, pruritus).
durabolin injection ® is not intended for use in ophthalmology, for vaginal and rectal administration.