Of anthelmintic drugs durabolin price of broad-spectrum; It is most effective when enterobioze and trihotsefaleze. Causing irreversible damage glucose utilization depletes glycogen in tissues of worms, prevents the synthesis of cellular tubulin and inhibits the synthesis of adenosine triphosphate (ATP).Practically not absorbed durabolin price in the intestine. Half-life of 2.5-5.5 hours. Communication with plasma proteins – 90%. Unevenly distributed in organs, accumulate in adipose tissue, liver, helminth larvae, is metabolized to the 2-amino derivative. More than 90% of the dose is excreted in the feces unchanged. Suck part (5-10%) excreted by the kidneys.
Indications for use:
Enterobiasis, Ascariasis, hookworm, strongyloidiasis, trichocephalosis, trihinelleh taeniasis, echinococcosis, multiple nematode alveokokkyaoz, kapillyaroz gnathostomiasis mixed helminth infections. Hypersensitivity, ulcerative colitis, Crohn’s disease, liver failure, children’s age (up to 2 years), pregnancy, lactation .
Dosage and administration:
Inside a small amount of water. Adults and children over 10 years enterobioze – single, 100 mg. Children aged 2 to 10 years odnokratno- 25-50 mg. In the case of high probability of re-infestation taken again after 2-4 weeks in the same dose. It is recommended nandrolone phenylpropionate that the simultaneous treatment of all members of the family. In ascariasis, trihotsefaleze, hookworm, taeniasis, strongiloidoze and mixed helminthiasis – in the morning and in the evening 100 mg for 3 days. When trichinosis 3 times a day, 200-400 mg for three days, and on day 4 of 10 – 3 x 400-500. When echinococcosis in the first 3 days – 500 mg 2 times a day over the next 3 days the dose is increased to 500 mg three times a day; subsequently increase the dose until a maximum (at the rate of 25-30 mg / kg / day) and a take 3-4 hours.
Side effects: Dizziness, nausea, and durabolin price abdominal pain. When used in high doses for a long time: vomiting, diarrhea, headache, allergic reactions (skin rash, urticaria, angioedema), increased activity of “liver” transaminases, hypercreatininemia, leukopenia, anemia , eosinophilia, hair loss, hematuria, tsiliddruriya.
Symptoms: abdominal pain, nausea, vomiting, diarrhea. When used in high doses for a long time: reversible hepatic dysfunction, hepatitis, neutropenia. Treatment: you need to remove the drug from the stomach, causing vomiting or gastric lavage, administration of activated charcoal.
Interaction with other drugs: Reduces the need for insulin in patients with diabetes. Avoid concomitant administration with lipophilic substances. Cimetidine may increase the blood concentration of carbamazepine and other inducers of metabolism -. Lower.
Chronic administration necessary to control the picture durabolin price of peripheral blood, liver and kidney function. Within days after taking the prohibited use of ethanol, fatty foods, not to prescribe a laxative. Be sure to periodically smear the anal area and feces after treatment: therapy is considered effective in the absence of helminths or eggs during the following days.
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